The Sorghum Adaptation in West Africa with a Genomics-Enabled Breeding Network (SAWAGEN) is a unique network of national researchers, international collaborators and farmer organizations aimed at leveraging capacity to develop and deliver demand-driven improved varieties to farmers. It is built on four separate platforms – local adaptation breeding, genetic mapping research, physiological mapping research, and broad adaptation breeding – and links researchers across those platforms in a hypothesis-driven, goal-oriented research approach. The SAWAGEN spans Senegal, Burkina Faso, Togo and Niger and reinforces existing regional breeding network initiatives to further accelerate interdisciplinary solutions to key crop improvement challenges across the Sahel.